World No. 1 pulls out with a right shoulder injury.
World No. 1 can defend his crown as Wimbledon will not require players to be vaccinated.
Two events are now on Roger Federer's 2022 calendar: Laver Cup and Basel.
The five-time Madrid champion announced that he'll take part in this year's event in Spain.
US Open champion will work with LTA head of women coaching in Madrid.
The 18-year-old has won three titles from his last five events.
Benoit Paire pulled out the posterior after bowing to Soonwoo Kwon at the Estoril Open.