The Tunisian says she took time to get over her loss to Vondrousova in the final of Wimbledon.
The Russian would like to keep the two top seeds from meeting in the final.
The 23-time major champion is ready to lay it all on the line in New York City.
Sweden's No. 1 player retires after failed attempt to reverse doping suspension.
"I love to play the game, I'm very passionate about it, and I want to be the best I possibly can be," says Caroline Wozniacki ahead of her US Open return.
"American tennis is in a great spot. It's been probably the best spot it has been in a really long time," US Open semifinalist Frances Tiafoe said.
World No. 1 will continue playing with a Babolat racquet until at least 2030.